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The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence

Antimicrobial peptides (AMPs) offer a promising solution to the antibiotic resistance crisis. However, an unresolved serious concern is that the evolution of resistance to therapeutic AMPs may generate cross-resistance to host AMPs, compromising a cornerstone of the innate immune response. We system...

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Detalles Bibliográficos
Autores principales: Jangir, Pramod K, Ogunlana, Lois, Szili, Petra, Czikkely, Marton, Shaw, Liam P, Stevens, Emily J, Yu, Yang, Yang, Qiue, Wang, Yang, Pál, Csaba, Walsh, Timothy R, MacLean, Craig R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129329/
https://www.ncbi.nlm.nih.gov/pubmed/37094804
http://dx.doi.org/10.7554/eLife.84395