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Optimal cancer evasion in a dynamic immune microenvironment generates diverse post-escape tumor antigenicity profiles
The failure of cancer treatments, including immunotherapy, continues to be a major obstacle in preventing durable remission. This failure often results from tumor evolution, both genotypic and phenotypic, away from sensitive cell states. Here, we propose a mathematical framework for studying the dyn...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129331/ https://www.ncbi.nlm.nih.gov/pubmed/37096883 http://dx.doi.org/10.7554/eLife.82786 |