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284 Generalizable Machine Learning Methods for Subtyping Individuals on National Health Databases: Case Studies Using Data from HRS, N3C, and All of Us

OBJECTIVES/GOALS: While disease subtypes are critical for precision medicine, most projects use unipartite clustering methods such as k-means which are not fully automated, do not provide statistical significance, and are difficult to interpret. These gaps were addressed through bipartite networks a...

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Detalles Bibliográficos
Autores principales: Bhavnani, Suresh K., Zhang, Weibin, Bao, Daniel, Hatch, Sandra, Reistetter, Timothy, Downer, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129454/
http://dx.doi.org/10.1017/cts.2023.340