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429 Eribulin Synergizes with STING Agonists by Enhancing Type 1 Interferon Expression and Improves Antitumor Efficacy as Combination Treatment

OBJECTIVES/GOALS: Triple-negative breast cancer (TNBC) is a subtype of breast cancer that lacks effective targeted treatment options. TNBC's greater degree of immunogenicity than other breast tumors makes immunotherapy a viable strategy. Strategies to improve the immunotherapy response includes...

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Detalles Bibliográficos
Autores principales: Takahashi-Ruiz, Leila, Fermaintt, Charles S., Wilkinson, Nancy, Chan, Peter Y., Mooberry, Susan L., Risinger, April L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129478/
http://dx.doi.org/10.1017/cts.2023.460