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481 Interactions between buprenorphine and norbuprenorphine in neonatal opioid withdrawal syndrome

OBJECTIVES/GOALS: Buprenorphine (BUP) is used for opioid use disorder during pregnancy but causes neonatal opioid withdrawal syndrome (NOWS). The goal of this study was to determine the contribution of the active metabolite, norbuprenorphine (NorBUP), to the development of NOWS when the parent drug,...

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Detalles Bibliográficos
Autores principales: Tobacyk, Julia, Parks, Brian J., Coward, Lori, Berquist, Michael D., Gorman, Gregory S., Brents, Lisa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129499/
http://dx.doi.org/10.1017/cts.2023.494