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272 Differential expression of two Plasmodium falciparum variant surface antigen families in Malian children with cerebral malaria compared to mild malaria

OBJECTIVES/GOALS: Recent in vitro evidence suggests that diverse parasite protein families called RIFINs and STEVORs are displayed on the surface of infected red blood cells and may have a role in severe malaria, but they remain sparsely studied in natural infections. We measured the RNA expression...

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Detalles Bibliográficos
Autores principales: Lawton, Jonathan G., Zhou, Albert E., Coulibaly, Drissa, Stucke, Emily M., Dara, Antoine, Laurens, Matthew B., Silva, Joana C., Thera, Mahamadou A., Travassos, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129581/
http://dx.doi.org/10.1017/cts.2023.330