440 Role of angiotensin II in SARS-CoV-2 pathophysiology in a hamster model of COVID-19

OBJECTIVES/GOALS: Hamsters develop COVID-19 similarly to people because the SARS-CoV-2 spike protein binds with high affinity to hamster ACE2 resulting in host cell entry and replication. Our goal was to establish a hamster model that mirrors the lung and brain pathophysiology observed in COVID-19....

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Detalles Bibliográficos
Autores principales: Stanic, Branka Milicic, Dugal, Nisha, Shults, Nataliia, Ji, Hong, de Souza, Aline M.A., Hawkins, Seth, Wu, Xie, Saavedra, Juan M., Sandberg, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Team Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129665/
http://dx.doi.org/10.1017/cts.2023.468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129665/
http://dx.doi.org/10.1017/cts.2023.468

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