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Drug Discovery Perspectives of Antisense Oligonucleotides

The era of innovative RNA therapies using antisense oligonucleotides (ASOs), siRNAs, and mRNAs is beginning. Since the emergence of the concept of ASOs in 1978, it took more than 20 years before they were developed into drugs for commercial use. Nine ASO drugs have been approved to date. However, th...

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Detalles Bibliográficos
Autor principal: Kim, Yeonjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129852/
https://www.ncbi.nlm.nih.gov/pubmed/36859811
http://dx.doi.org/10.4062/biomolther.2023.001