Ebastine impairs metastatic spread in triple-negative breast cancer by targeting focal adhesion kinase

We sought to investigate the utility of ebastine (EBA), a second-generation antihistamine with potent anti-metastatic properties, in the context of breast cancer stem cell (BCSC)-suppression in triple-negative breast cancer (TNBC). EBA binds to the tyrosine kinase domain of focal adhesion kinase (FA...

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Detalles Bibliográficos
Autores principales: Seo, Juyeon, Park, Minsu, Ko, Dongmi, Kim, Seongjae, Park, Jung Min, Park, Soeun, Nam, Kee Dal, Farrand, Lee, Yang, Jinsol, Seok, Chaok, Jung, Eunsun, Kim, Yoon-Jae, Kim, Ji Young, Seo, Jae Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130003/
https://www.ncbi.nlm.nih.gov/pubmed/37185776
http://dx.doi.org/10.1007/s00018-023-04760-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130003/
https://www.ncbi.nlm.nih.gov/pubmed/37185776
http://dx.doi.org/10.1007/s00018-023-04760-5

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