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Isthmin-1 (Ism1) modulates renal branching morphogenesis and mesenchyme condensation during early kidney development

The outgrowth of epithelial bud followed by reiterated bifurcations during renal development is driven by the ligand-receptor interactions between the epithelium and the surrounding mesenchyme. Here, by exploring ligand-receptor interactions in E10.5 and E11.5 kidneys by single cell RNA-seq, we find...

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Detalles Bibliográficos
Autores principales: Gao, Ge, Li, Xiaoping, Jiang, Zhixin, Osorio, Liliana, Tang, Ying Lam, Yu, Xueqing, Jin, Guoxiang, Zhou, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130008/
https://www.ncbi.nlm.nih.gov/pubmed/37185772
http://dx.doi.org/10.1038/s41467-023-37992-x