An unbiased AAV-STARR-seq screen revealing the enhancer activity map of genomic regions in the mouse brain in vivo

Enhancers are important cis-regulatory elements controlling cell-type specific expression patterns of genes. Furthermore, combinations of enhancers and minimal promoters are utilized to construct small, artificial promoters for gene delivery vectors. Large-scale functional screening methodology to c...

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Detalles Bibliográficos
Autores principales: Chan, Ya-Chien, Kienle, Eike, Oti, Martin, Di Liddo, Antonella, Mendez-Lago, Maria, Aschauer, Dominik F., Peter, Manuel, Pagani, Michaela, Arnold, Cosmas, Vonderheit, Andreas, Schön, Christian, Kreuz, Sebastian, Stark, Alexander, Rumpel, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130037/
https://www.ncbi.nlm.nih.gov/pubmed/37185990
http://dx.doi.org/10.1038/s41598-023-33448-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130037/
https://www.ncbi.nlm.nih.gov/pubmed/37185990
http://dx.doi.org/10.1038/s41598-023-33448-w

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