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An unbiased AAV-STARR-seq screen revealing the enhancer activity map of genomic regions in the mouse brain in vivo
Enhancers are important cis-regulatory elements controlling cell-type specific expression patterns of genes. Furthermore, combinations of enhancers and minimal promoters are utilized to construct small, artificial promoters for gene delivery vectors. Large-scale functional screening methodology to c...
Autores principales: | Chan, Ya-Chien, Kienle, Eike, Oti, Martin, Di Liddo, Antonella, Mendez-Lago, Maria, Aschauer, Dominik F., Peter, Manuel, Pagani, Michaela, Arnold, Cosmas, Vonderheit, Andreas, Schön, Christian, Kreuz, Sebastian, Stark, Alexander, Rumpel, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130037/ https://www.ncbi.nlm.nih.gov/pubmed/37185990 http://dx.doi.org/10.1038/s41598-023-33448-w |
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