Cargando…

Down-regulation of DNA key protein-FEN1 inhibits OSCC growth by affecting immunosuppressive phenotypes via IFN-γ/JAK/STAT-1

Oral squamous cell carcinoma (OSCC) escape from the immune system is mediated through several immunosuppressive phenotypes that are critical to the initiation and progression of tumors. As a hallmark of cancer, DNA damage repair is closely related to changes in the immunophenotypes of tumor cells. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shimeng, Wang, Xiangjian, Sun, Jun, Yang, Jin, Wu, Deyang, Wu, Fanglong, Zhou, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130046/
https://www.ncbi.nlm.nih.gov/pubmed/37185662
http://dx.doi.org/10.1038/s41368-023-00221-8