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Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis

The bone marrow contains various populations of skeletal stem cells (SSCs) in the stromal compartment, which are important regulators of bone formation. It is well-described that leptin receptor (LepR)(+) perivascular stromal cells provide a major source of bone-forming osteoblasts in adult and aged...

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Detalles Bibliográficos
Autores principales: Matsushita, Yuki, Liu, Jialin, Chu, Angel Ka Yan, Tsutsumi-Arai, Chiaki, Nagata, Mizuki, Arai, Yuki, Ono, Wanida, Yamamoto, Kouhei, Saunders, Thomas L., Welch, Joshua D., Ono, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130060/
https://www.ncbi.nlm.nih.gov/pubmed/37185464
http://dx.doi.org/10.1038/s41467-023-38034-2