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The asymmetrical ESR1 signaling in muscle progenitor cells determines the progression of adolescent idiopathic scoliosis

Adolescent Idiopathic Scoliosis (AIS) is a common pediatric skeletal disease highly occurred in females. The pathogenesis of AIS has not been fully elucidated. Here, we reveal that ESR1 (Estrogen Receptor 1) expression declines in muscle stem/progenitor cells at the concave side of AIS patients. Fur...

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Detalles Bibliográficos
Autores principales: Shao, Xiexiang, Fu, Xin, Yang, Jingfan, Sui, Wenyuan, Li, Sheng, Yang, Wenjun, Lin, Xingzuan, Zhang, Yuanyuan, Jia, Minzhi, Liu, Huan, Liu, Wei, Han, Lili, Yu, Yang, Deng, Yaolong, Zhang, Tianyuan, Yang, Junlin, Hu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130095/
https://www.ncbi.nlm.nih.gov/pubmed/37185898
http://dx.doi.org/10.1038/s41421-023-00531-5