Immunization with a Trypanosoma cruzi cyclophilin-19 deletion mutant protects against acute Chagas disease in mice

Human infection with the protozoan parasite Trypanosoma cruzi causes Chagas disease for which there are no prophylactic vaccines. Cyclophilin 19 is a secreted cis-trans peptidyl isomerase expressed in all life stages of Trypanosoma cruzi. This protein in the insect stage leads to the inactivation of...

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Detalles Bibliográficos
Autores principales: Jha, Bijay Kumar, Varikuti, Sanjay, Verma, Chaitenya, Shivahare, Rahul, Bishop, Nicholas, Dos Santos, Gregory P., McDonald, Jacquelyn, Sur, Aakash, Myler, Peter J., Schenkman, Sergio, Satoskar, Abhay R., McGwire, Bradford S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130101/
https://www.ncbi.nlm.nih.gov/pubmed/37185599
http://dx.doi.org/10.1038/s41541-023-00647-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130101/
https://www.ncbi.nlm.nih.gov/pubmed/37185599
http://dx.doi.org/10.1038/s41541-023-00647-5

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