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Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis

This study aimed to find any ambiguous genetic outlier for “oligodendroglioma, IDH-mutant and 1p/19q-codeleted (O_IDH_mut)” and “astrocytoma, IDH-mutant (A_IDH_mut)” and to redefine the genetic landscape and prognostic factors of IDH-mutant gliomas. Next-generation sequencing (NGS) using a brain tum...

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Detalles Bibliográficos
Autores principales: Lee, Kwanghoon, Kim, Seong-Ik, Kim, Eric Eunshik, Shim, Yu-Mi, Won, Jae-Kyung, Park, Chul-Kee, Choi, Seung Hong, Yun, Hongseok, Lee, Hyunju, Park, Sung-Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130138/
https://www.ncbi.nlm.nih.gov/pubmed/37185778
http://dx.doi.org/10.1038/s41598-023-32153-y