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Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis
This study aimed to find any ambiguous genetic outlier for “oligodendroglioma, IDH-mutant and 1p/19q-codeleted (O_IDH_mut)” and “astrocytoma, IDH-mutant (A_IDH_mut)” and to redefine the genetic landscape and prognostic factors of IDH-mutant gliomas. Next-generation sequencing (NGS) using a brain tum...
Autores principales: | Lee, Kwanghoon, Kim, Seong-Ik, Kim, Eric Eunshik, Shim, Yu-Mi, Won, Jae-Kyung, Park, Chul-Kee, Choi, Seung Hong, Yun, Hongseok, Lee, Hyunju, Park, Sung-Hye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130138/ https://www.ncbi.nlm.nih.gov/pubmed/37185778 http://dx.doi.org/10.1038/s41598-023-32153-y |
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