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Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling

Evidence shows that short-chain fatty acids (SCFAs) play an important role in health maintenance and disease development. In particular, butyrate is known to induce apoptosis and autophagy. However, it remains largely unclear whether butyrate can regulate cell ferroptosis, and the mechanism by which...

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Detalles Bibliográficos
Autores principales: Wang, GuoYan, Qin, SenLin, Chen, Lei, Geng, HuiJun, Zheng, YiNing, Xia, Chao, Yao, JunHu, Deng, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130170/
https://www.ncbi.nlm.nih.gov/pubmed/37185889
http://dx.doi.org/10.1038/s41419-023-05778-0