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Teasing out missing reactions in genome-scale metabolic networks through hypergraph learning

GEnome-scale Metabolic models (GEMs) are powerful tools to predict cellular metabolism and physiological states in living organisms. However, due to our imperfect knowledge of metabolic processes, even highly curated GEMs have knowledge gaps (e.g., missing reactions). Existing gap-filling methods ty...

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Detalles Bibliográficos
Autores principales: Chen, Can, Liao, Chen, Liu, Yang-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130184/
https://www.ncbi.nlm.nih.gov/pubmed/37185345
http://dx.doi.org/10.1038/s41467-023-38110-7