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Molecular mechanism of tRNA binding by the Escherichia coli N7 guanosine methyltransferase TrmB

Among the large and diverse collection of tRNA modifications, 7-methylguanosine (m(7)G) is frequently found in the tRNA variable loop at position 46. This modification is introduced by the TrmB enzyme, which is conserved in bacteria and eukaryotes. However, the molecular determinants and the mechani...

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Detalles Bibliográficos
Autores principales: Schultz, Sarah K., Meadows, Kieran, Kothe, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130221/
https://www.ncbi.nlm.nih.gov/pubmed/36933808
http://dx.doi.org/10.1016/j.jbc.2023.104612