Single-molecule dynamics of DNA gyrase in evolutionarily distant bacteria Mycobacterium tuberculosis and Escherichia coli

DNA gyrase is an essential nucleoprotein motor present in all bacteria and is a major target for antibiotic treatment of Mycobacterium tuberculosis (MTB) infection. Gyrase hydrolyzes ATP to add negative supercoils to DNA using a strand passage mechanism that has been investigated using biophysical a...

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Detalles Bibliográficos
Autores principales: Galvin, Cooper J., Hobson, Matthew, Meng, Jonathan Xianglong, Ierokomos, Athena, Ivanov, Ivan E., Berger, James M., Bryant, Zev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130225/
https://www.ncbi.nlm.nih.gov/pubmed/36775125
http://dx.doi.org/10.1016/j.jbc.2023.103003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130225/
https://www.ncbi.nlm.nih.gov/pubmed/36775125
http://dx.doi.org/10.1016/j.jbc.2023.103003

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