Cargando…

The CDR3 region as the major driver of TREM-1 interaction with its ligands, an in silico characterization

The triggering receptor expressed on myeloid cells-1 (TREM-1) is a pattern recognition receptor heavily investigated in infectious and non-infectious diseases. Because of its role in amplifying inflammation, TREM-1 has been explored as a diagnostic/prognostic biomarker. Further, as the receptor has...

Descripción completa

Detalles Bibliográficos
Autores principales: de Oliveira Matos, Amanda, dos Santos Dantas, Pedro Henrique, Colmenares, Mike Telemaco Contreras, Sartori, Geraldo Rodrigues, Silva-Sales, Marcelle, Da Silva, João Herminio Martins, Neves, Bruno Junior, Andrade, Carolina Horta, Sales-Campos, Helioswilton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130352/
https://www.ncbi.nlm.nih.gov/pubmed/37122631
http://dx.doi.org/10.1016/j.csbj.2023.04.008