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miR-1246 in tumor extracellular vesicles promotes metastasis via increased tumor cell adhesion and endothelial cell barrier destruction

BACKGROUND: Tumor blood vessels play a key role in tumor metastasis. We have previously reported that tumor endothelial cells (TECs) exhibit abnormalities compared to normal endothelial cells. However, it is unclear how TECs acquire these abnormalities. Tumor cells secrete extracellular vesicles (EV...

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Detalles Bibliográficos
Autores principales: Morimoto, Masahiro, Maishi, Nako, Tsumita, Takuya, Alam, Mohammad Towfik, Kikuchi, Hiroshi, Hida, Yasuhiro, Yoshioka, Yusuke, Ochiya, Takahiro, Annan, Dorcas A., Takeda, Ryo, Kitagawa, Yoshimasa, Hida, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130374/
https://www.ncbi.nlm.nih.gov/pubmed/37124539
http://dx.doi.org/10.3389/fonc.2023.973871