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Time-resolved single-cell transcriptomics reveals the landscape and dynamics of hepatic cells in sepsis-induced acute liver dysfunction

BACKGROUND & AIMS: Sepsis-induced acute liver dysfunction often occurs early in sepsis and can exacerbate the pathology by triggering multiple organ dysfunction and increasing lethality. Nevertheless, our understanding of the cellular heterogeneity and dynamic regulation of major nonparenchymal...

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Detalles Bibliográficos
Autores principales: Chen, Gan, Ren, Chao, Xiao, Yao, Wang, Yujing, Yao, Renqi, Wang, Quan, You, Guoxing, Lu, Mingzi, Yan, Shaoduo, Zhang, Xiaoyong, Zhang, Jun, Yao, Yongming, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130477/
https://www.ncbi.nlm.nih.gov/pubmed/37122356
http://dx.doi.org/10.1016/j.jhepr.2023.100718