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Non-viral gene therapy using RNA interference with PDGFR-α mediated epithelial-mesenchymal transformation for proliferative vitreoretinopathy

Fibrotic eye diseases, a series of severe oculopathy, that will destroy normal ocular refractive media and imaging structures. It is characterized by the transformation of the epithelial cells into mesenchyme cells. Proliferative vitreoretinopathy (PVR) is one of these representative diseases. In th...

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Detalles Bibliográficos
Autores principales: Wang, Jiahao, Zhao, Peiyi, Chen, Zhirong, Wang, Hui, Wang, Yajia, Lin, Quankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130499/
https://www.ncbi.nlm.nih.gov/pubmed/37122836
http://dx.doi.org/10.1016/j.mtbio.2023.100632