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Histaminergic neurotransmission in aging and Alzheimer's disease: A review of therapeutic opportunities and gaps

INTRODUCTION: Alzheimer's disease (AD) is a progressive neurodegenerative disorderfeaturing a brain accumulation of extracellular β‐amyloidplaques (Aβ) and intracellular neurofibrillary tautangles (NFTs). Although cognitive decline is a disease‐defining symptom of AD, sleep dysfunction, a commo...

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Detalles Bibliográficos
Autores principales: Satpati, Abhijit, Neylan, Thomas, Grinberg, Lea T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130560/
https://www.ncbi.nlm.nih.gov/pubmed/37123051
http://dx.doi.org/10.1002/trc2.12379