MAP kinase activating death domain deficiency is a novel cause of impaired lymphocyte cytotoxicity

Most hereditary forms of hemophagocytic lymphohistiocytosis (HLH) are caused by defects of cytotoxicity, including the vesicle trafficking disorder Griscelli syndrome type 2 (GS2, RAB27A deficiency). Deficiency of the mitogen-activated protein kinase activating death domain protein (MADD) results in...

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Detalles Bibliográficos
Autores principales: Schütze, Kerstin, Groß, Miriam, Cornils, Kerstin, Wustrau, Katharina, Schneppenheim, Sonja, Lenhartz, Henning, Korenke, G. Christoph, Janka, Gritta, Ledig, Svea, Müller, Ingo, Ehl, Stephan, Lehmberg, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Stimulus Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130601/
https://www.ncbi.nlm.nih.gov/pubmed/36206192
http://dx.doi.org/10.1182/bloodadvances.2022008195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130601/
https://www.ncbi.nlm.nih.gov/pubmed/36206192
http://dx.doi.org/10.1182/bloodadvances.2022008195

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