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Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8(+) T cells in HIV infection

BACKGROUND: CD8(+) T cells equipped with a full arsenal of antiviral effector functions are critical for effective immune control of HIV-1. It has nonetheless remained unclear how best to elicit such potent cellular immune responses in the context of immunotherapy or vaccination. HIV-2 has been asso...

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Detalles Bibliográficos
Autores principales: Cabral-Piccin, Mariela P., Papagno, Laura, Lahaye, Xavier, Perdomo-Celis, Federico, Volant, Stevenn, White, Eoghann, Monceaux, Valérie, Llewellyn-Lacey, Sian, Fromentin, Rémi, Price, David A., Chomont, Nicolas, Manel, Nicolas, Saez-Cirion, Asier, Appay, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130611/
https://www.ncbi.nlm.nih.gov/pubmed/37058769
http://dx.doi.org/10.1016/j.ebiom.2023.104557