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Cerebrospinal fluid proteomics in recent-onset Narcolepsy type 1 reveals activation of the complement system

INTRODUCTION: Narcolepsy type 1 (NT1) is a rare, chronic and disabling neurological disease causing excessive daytime sleepiness and cataplexy. NT1 is characterized pathologically by an almost complete loss of neurons producing the orexin neuropeptides in the lateral hypothalamus. Genetic and enviro...

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Detalles Bibliográficos
Autores principales: Ayoub, Ikram, Dauvilliers, Yves, Barateau, Lucie, Vermeulen, Thaïs, Mouton-Barbosa, Emmanuelle, Marcellin, Marlène, Gonzalez-de-Peredo, Anne, Gross, Catharina C., Saoudi, Abdelhadi, Liblau, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130643/
https://www.ncbi.nlm.nih.gov/pubmed/37122721
http://dx.doi.org/10.3389/fimmu.2023.1108682