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The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand

Recognition of integrins by CD62P has not been reported and this motivated a docking simulation using integrin αvβ3 as a target. We predicted that the C-type lectin domain of CD62P functions as a potential integrin ligand and observed that it specifically bound to soluble β3 and β1 integrins. Known...

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Detalles Bibliográficos
Autores principales: Takada, Yoko K, Simon, Scott I, Takada, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130748/
https://www.ncbi.nlm.nih.gov/pubmed/37184585
http://dx.doi.org/10.26508/lsa.202201747