BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer

BAZ2A represses rRNA genes (rDNA) that are transcribed by RNA polymerase I. In prostate cancer (PCa), BAZ2A function goes beyond this role because it represses genes frequently silenced in metastatic disease. However, the mechanisms of this BAZ2A-mediated repression remain elusive. Here, we show tha...

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Detalles Bibliográficos
Autores principales: Roganowicz, Marcin, Bär, Dominik, Bersaglieri, Cristiana, Aprigliano, Rossana, Santoro, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130768/
https://www.ncbi.nlm.nih.gov/pubmed/37184661
http://dx.doi.org/10.26508/lsa.202301950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130768/
https://www.ncbi.nlm.nih.gov/pubmed/37184661
http://dx.doi.org/10.26508/lsa.202301950

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