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BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer
BAZ2A represses rRNA genes (rDNA) that are transcribed by RNA polymerase I. In prostate cancer (PCa), BAZ2A function goes beyond this role because it represses genes frequently silenced in metastatic disease. However, the mechanisms of this BAZ2A-mediated repression remain elusive. Here, we show tha...
Autores principales: | Roganowicz, Marcin, Bär, Dominik, Bersaglieri, Cristiana, Aprigliano, Rossana, Santoro, Raffaella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130768/ https://www.ncbi.nlm.nih.gov/pubmed/37184661 http://dx.doi.org/10.26508/lsa.202301950 |
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