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Vitamin D reduces pain and cartilage destruction in knee osteoarthritis animals through inhibiting the matrix metalloprotease (MMPs) expression

AIM OF THE STUDY: In this study, we investigated the therapeutic potential of vitamin D (VITD) in OA Wistar rats induced by anterior cruciate ligament transection combined with medial meniscectomy (ACLT + MMx). In ACLT + MMx-induced OA rats, pain severity, cartilage destruction, inflammatory cytokin...

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Detalles Bibliográficos
Autores principales: Busa, Prabhakar, Huang, Niancih, Kuthati, Yaswanth, Wong, Chih-Shung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130884/
https://www.ncbi.nlm.nih.gov/pubmed/37123896
http://dx.doi.org/10.1016/j.heliyon.2023.e15268