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Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine

High-grade serous ovarian carcinoma (HGSOC) is one of the most fatal gynecological cancers and has no effective prevention strategies. Herein, we demonstrated that progesterone significantly inhibited the occurrence, metastasis, and ascites of ovarian cancer in vivo, and the tumor inhibition effect...

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Detalles Bibliográficos
Autores principales: Wu, Nayiyuan, Zhang, Xiaoye, Wang, Zhibin, Zhang, Xiu, Fang, Chao, Li, He, Zhu, Miaochen, Wang, Ying, Liao, Qianjin, Chu, Tang-Yuan, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130919/
https://www.ncbi.nlm.nih.gov/pubmed/37123232
http://dx.doi.org/10.1016/j.isci.2023.106523