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Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine
High-grade serous ovarian carcinoma (HGSOC) is one of the most fatal gynecological cancers and has no effective prevention strategies. Herein, we demonstrated that progesterone significantly inhibited the occurrence, metastasis, and ascites of ovarian cancer in vivo, and the tumor inhibition effect...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130919/ https://www.ncbi.nlm.nih.gov/pubmed/37123232 http://dx.doi.org/10.1016/j.isci.2023.106523 |