Fibroblast growth factor-21 is required for weight loss induced by the glucagon-like peptide-1 receptor agonist liraglutide in male mice fed high carbohydrate diets

OBJECTIVE: Glucagon-like peptide-1 receptor (GLP-1R) agonists (GLP-1RA) and fibroblast growth factor-21 (FGF21) confer similar metabolic benefits. GLP-1RA induce FGF21, leading us to investigate mechanisms engaged by the GLP-1RA liraglutide to increase FGF21 levels and the metabolic relevance of lir...

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Detalles Bibliográficos
Autores principales: Le, Thao D.V., Fathi, Payam, Watters, Amanda B., Ellis, Blair J., Besing, Gai-Linn K., Bozadjieva-Kramer, Nadejda, Perez, Misty B., Sullivan, Andrew I., Rose, Jesse P., Baggio, Laurie L., Koehler, Jacqueline, Brown, Jennifer L., Bales, Michelle B., Nwaba, Kaitlyn G., Campbell, Jonathan E., Drucker, Daniel J., Potthoff, Matthew J., Seeley, Randy J., Ayala, Julio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131131/
https://www.ncbi.nlm.nih.gov/pubmed/37030441
http://dx.doi.org/10.1016/j.molmet.2023.101718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131131/
https://www.ncbi.nlm.nih.gov/pubmed/37030441
http://dx.doi.org/10.1016/j.molmet.2023.101718

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