Charge shielding effects of PEG bound to NH(2)-terminated PAMAM dendrimers – an experimental approach

Cationic poly(amido amine) (PAMAM) dendrimers exhibit great potential for use in drug delivery, but their high charge density leads to an inherent cytotoxicity. To increase biocompatibility, many studies have attached poly(ethylene glycol) (PEG) chains to the dendrimer surface. It is unclear how the...

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Detalles Bibliográficos
Autores principales: Johnston, Brandon M., Grodzinsky, Alan J., Hammond, Paula T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131161/
https://www.ncbi.nlm.nih.gov/pubmed/37038739
http://dx.doi.org/10.1039/d2sm01698b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131161/
https://www.ncbi.nlm.nih.gov/pubmed/37038739
http://dx.doi.org/10.1039/d2sm01698b

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