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IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii

Interleukin-18 (IL-18) promotes natural killer (NK) and T cell production of interferon (IFN)-γ, a key factor in resistance to Toxoplasma gondii, but previous work has shown a limited role for endogenous IL-18 in control of this parasite. Although infection with T. gondii results in release of IL-18...

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Detalles Bibliográficos
Autores principales: Clark, Joseph T., Weizman, Orr-El, Aldridge, Daniel L., Shallberg, Lindsey A., Eberhard, Julia, Lanzar, Zachary, Wasche, Devon, Huck, John D., Zhou, Ting, Ring, Aaron M., Hunter, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131179/
https://www.ncbi.nlm.nih.gov/pubmed/36827187
http://dx.doi.org/10.1016/j.celrep.2023.112147