Cargando…
IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii
Interleukin-18 (IL-18) promotes natural killer (NK) and T cell production of interferon (IFN)-γ, a key factor in resistance to Toxoplasma gondii, but previous work has shown a limited role for endogenous IL-18 in control of this parasite. Although infection with T. gondii results in release of IL-18...
Autores principales: | Clark, Joseph T., Weizman, Orr-El, Aldridge, Daniel L., Shallberg, Lindsey A., Eberhard, Julia, Lanzar, Zachary, Wasche, Devon, Huck, John D., Zhou, Ting, Ring, Aaron M., Hunter, Christopher A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131179/ https://www.ncbi.nlm.nih.gov/pubmed/36827187 http://dx.doi.org/10.1016/j.celrep.2023.112147 |
Ejemplares similares
-
Toxoplasma gondii Dissemination in the Brain Is Facilitated by Infiltrating Peripheral Immune Cells
por: Schneider, Christine A., et al.
Publicado: (2022) -
IL-18BP is a secreted immune checkpoint and barrier to IL-18
immunotherapy
por: Zhou, Ting, et al.
Publicado: (2020) -
PD-1 and CTLA-4 exert additive control of effector regulatory T cells at homeostasis
por: Pereira, Joseph A., et al.
Publicado: (2023) -
Role of IL‐18 in atopic asthma is determined by balance of IL‐18/IL‐18BP/IL‐18R
por: Zhang, Huiyun, et al.
Publicado: (2017) -
Toxoplasma gondii
por: Liesenfeld, Oliver
Publicado: (2009)