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Direct Selection of DNA-Encoded Libraries for Biased Agonists of GPCRs on Live Cells
[Image: see text] G protein-coupled receptors (GPCRs) are the largest superfamily of human membrane target proteins for approved drugs. GPCR ligands can have a complex array of pharmacological activities. Among these activities, biased agonists have potential to serve as both chemical probes to unde...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131204/ https://www.ncbi.nlm.nih.gov/pubmed/37124302 http://dx.doi.org/10.1021/jacsau.2c00674 |