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Direct Selection of DNA-Encoded Libraries for Biased Agonists of GPCRs on Live Cells

[Image: see text] G protein-coupled receptors (GPCRs) are the largest superfamily of human membrane target proteins for approved drugs. GPCR ligands can have a complex array of pharmacological activities. Among these activities, biased agonists have potential to serve as both chemical probes to unde...

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Detalles Bibliográficos
Autores principales:	Cai, Bo, El Daibani, Amal, Bai, Yuntian, Che, Tao, Krusemark, Casey J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131204/ https://www.ncbi.nlm.nih.gov/pubmed/37124302 http://dx.doi.org/10.1021/jacsau.2c00674

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