Cargando…

Direct Selection of DNA-Encoded Libraries for Biased Agonists of GPCRs on Live Cells

[Image: see text] G protein-coupled receptors (GPCRs) are the largest superfamily of human membrane target proteins for approved drugs. GPCR ligands can have a complex array of pharmacological activities. Among these activities, biased agonists have potential to serve as both chemical probes to unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Bo, El Daibani, Amal, Bai, Yuntian, Che, Tao, Krusemark, Casey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131204/
https://www.ncbi.nlm.nih.gov/pubmed/37124302
http://dx.doi.org/10.1021/jacsau.2c00674

Ejemplares similares