Decoding the Roles of Amyloid-β (1–42)’s Key Oligomerization Domains toward Designing Epitope-Specific Aggregation Inhibitors

[Image: see text] Fibrillar amyloid aggregates are the pathological hallmarks of multiple neurodegenerative diseases. The amyloid-β (1–42) protein, in particular, is a major component of senile plaques in the brains of patients with Alzheimer’s disease and a primary target for disease treatment. Det...

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Detalles Bibliográficos
Autores principales: Im, Dongjoon, Kim, Soohyeong, Yoon, Gyusub, Hyun, Da Gyeong, Eom, Yu-Gon, Lee, Ye Eun, Sohn, Chang Ho, Choi, Jeong-Mo, Kim, Hugh I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131210/
https://www.ncbi.nlm.nih.gov/pubmed/37124297
http://dx.doi.org/10.1021/jacsau.2c00668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131210/
https://www.ncbi.nlm.nih.gov/pubmed/37124297
http://dx.doi.org/10.1021/jacsau.2c00668

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