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Decoding the Roles of Amyloid-β (1–42)’s Key Oligomerization Domains toward Designing Epitope-Specific Aggregation Inhibitors
[Image: see text] Fibrillar amyloid aggregates are the pathological hallmarks of multiple neurodegenerative diseases. The amyloid-β (1–42) protein, in particular, is a major component of senile plaques in the brains of patients with Alzheimer’s disease and a primary target for disease treatment. Det...
Autores principales: | Im, Dongjoon, Kim, Soohyeong, Yoon, Gyusub, Hyun, Da Gyeong, Eom, Yu-Gon, Lee, Ye Eun, Sohn, Chang Ho, Choi, Jeong-Mo, Kim, Hugh I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131210/ https://www.ncbi.nlm.nih.gov/pubmed/37124297 http://dx.doi.org/10.1021/jacsau.2c00668 |
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