Safety and preservation of cardiac function following therapeutic vaccination against Trypanosoma cruzi in rhesus macaques

BACKGROUND: Chronic Chagasic cardiomyopathy is responsible for a large disease burden in the Americas, and a therapeutic vaccine would be highly desirable. We tested the safety and efficacy of a therapeutic DNA vaccine encoding antigens TSA-1 and Tc24 for preventing cardiac alterations in experiment...

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Detalles Bibliográficos
Autores principales: Dumonteil, Eric, Herrera, Claudia, Marx, Preston A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131272/
https://www.ncbi.nlm.nih.gov/pubmed/36210315
http://dx.doi.org/10.1016/j.jmii.2022.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131272/
https://www.ncbi.nlm.nih.gov/pubmed/36210315
http://dx.doi.org/10.1016/j.jmii.2022.09.003

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