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Safety and preservation of cardiac function following therapeutic vaccination against Trypanosoma cruzi in rhesus macaques
BACKGROUND: Chronic Chagasic cardiomyopathy is responsible for a large disease burden in the Americas, and a therapeutic vaccine would be highly desirable. We tested the safety and efficacy of a therapeutic DNA vaccine encoding antigens TSA-1 and Tc24 for preventing cardiac alterations in experiment...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131272/ https://www.ncbi.nlm.nih.gov/pubmed/36210315 http://dx.doi.org/10.1016/j.jmii.2022.09.003 |