Oncogenic role of copper‑induced cell death‑associated protein DLD in human cancer: A pan‑cancer analysis and experimental verification

Copper ions can bind directly to lipoylated components of the tricarboxylic acid (TCA) cycle, triggering the aggregation of mitochondrial lipoylated proteins and the destabilization of Fe-S cluster proteins, resulting in copper-dependent cell death. Dihydrolipoamide dehydrogenase (DLD) is a key prot...

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Detalles Bibliográficos
Autores principales: Qi, Han, Zhu, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131276/
https://www.ncbi.nlm.nih.gov/pubmed/37123026
http://dx.doi.org/10.3892/ol.2023.13800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131276/
https://www.ncbi.nlm.nih.gov/pubmed/37123026
http://dx.doi.org/10.3892/ol.2023.13800

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