Acetaldehyde via CGRP receptor and TRPA1 in Schwann cells mediates ethanol-evoked periorbital mechanical allodynia in mice: relevance for migraine

BACKGROUND: Ingestion of alcoholic beverages is a known trigger of migraine attacks. However, whether and how ethanol exerts its pro-migraine action remains poorly known. Ethanol stimulates the transient receptor potential vanilloid 1 (TRPV1) channel, and its dehydrogenized metabolite, acetaldehyde,...

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Detalles Bibliográficos
Autores principales: Landini, Lorenzo, Souza Monteiro de Araujo, Daniel, Chieca, Martina, De Siena, Gaetano, Bellantoni, Elisa, Geppetti, Pierangelo, Nassini, Romina, De Logu, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131321/
https://www.ncbi.nlm.nih.gov/pubmed/37101198
http://dx.doi.org/10.1186/s12929-023-00922-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131321/
https://www.ncbi.nlm.nih.gov/pubmed/37101198
http://dx.doi.org/10.1186/s12929-023-00922-6

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