Mesenchymal stem cells reversibly de-differentiate myofibroblasts to fibroblast-like cells by inhibiting the TGF-β-SMAD2/3 pathway

BACKGROUND: Myofibroblasts (MFB), one of the major effectors of pathologic fibrosis, mainly derived from the activation of fibroblast to myofibroblast transition (FMT). Although MFBs were historically considered terminally differentiated cells, their potential for de-differentiation was recently rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Ruohao, Wu, Miao, Wang, Yawen, Li, Chao, Zeng, Lingji, Wang, Yulian, Xiao, Maozhi, Chen, Xiaomei, Geng, Suxia, Lai, Peilong, Du, Xin, Weng, Jianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131436/
https://www.ncbi.nlm.nih.gov/pubmed/37098464
http://dx.doi.org/10.1186/s10020-023-00630-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131436/
https://www.ncbi.nlm.nih.gov/pubmed/37098464
http://dx.doi.org/10.1186/s10020-023-00630-9

Ejemplares similares