Curcumin attenuates hydroxychloroquine-mediated apoptosis and oxidative stress via the inhibition of TRPM2 channel signalling pathways in a retinal pigment epithelium cell line

PURPOSE: Hydroxychloroquine (HCQ) is used in the treatment of several diseases, such as malaria, Sjögren's disease, Covid-19, and rheumatoid arthritis. However, HCQ induces retinal pigment epithelium death via the excessive increase of cytosolic (cROS) and mitochondrial (mROS) free oxygen radic...

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Detalles Bibliográficos
Autores principales: Ertuğrul, Alper, Özkaya, Dilek, Nazıroğlu, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131512/
https://www.ncbi.nlm.nih.gov/pubmed/37099129
http://dx.doi.org/10.1007/s00417-023-06082-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131512/
https://www.ncbi.nlm.nih.gov/pubmed/37099129
http://dx.doi.org/10.1007/s00417-023-06082-5

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