Thymidine phosphorylase facilitates retinoic acid inducible gene-I induced endothelial dysfunction

Activation of nucleic acid sensors in endothelial cells (ECs) has been shown to drive inflammation across pathologies including cancer, atherosclerosis and obesity. We previously showed that enhancing cytosolic DNA sensing by inhibiting three prime exonuclease 1 (TREX1) in ECs led to EC dysfunction...

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Detalles Bibliográficos
Autores principales: Baris, Adrian, Fraile-Bethencourt, Eugenia, Eubanks, Jaiden, Khou, Sokchea, Anand, Sudarshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131517/
https://www.ncbi.nlm.nih.gov/pubmed/37100811
http://dx.doi.org/10.1038/s41419-023-05821-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131517/
https://www.ncbi.nlm.nih.gov/pubmed/37100811
http://dx.doi.org/10.1038/s41419-023-05821-0

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